In the emerging country, food intake of young children is often insufficient for growth. Macronutrients and micronutrients are necessary for the growth and development of children; children are at increased need for nutrients. Poor appetite may also be a result of nutritional deficiencies, and therefore, it can be both a cause and a consequence of malnutrition. On the other hand, because of conditions like infections they are at a higher risk for loss of appetite. Children with low appetite usually do not get sufficient amounts of nutrients, and as a result, may encounter growth failure, a condition that can seriously affect their current health and future well-being. Therefore, administration of multiple micronutrients may be advantageous in cases of growth failure and poor appetite.

Vitamin A
Vitamin A promotes normal growth and development; tissue and bone repair; healthy skin, eyes, and immune responses. Good sources include milk, cheese, eggs, and yellow-to-orange vegetables like carrots, yams, and squash. Vitamin A deficiency affects about 190 million preschool-age children, mostly from Africa and South-East Asia. In infants and children, vitamin A is essential to support rapid growth and to help combat infections. Inadequate intakes of vitamin A may lead to vitamin A deficiency which can cause visual impairment in the form of night blindness and may increase the risk of illness and death from childhood infections, including measles and those causing diarrhea.

Vitamin Bs
- Vitamin B1
Vitamin B1 is responsible for energy production in your child’s body. Vitamin B1 function:
• This vitamin is crucial for converting sugar and other carbohydrates into energy
• It protects the nervous system from any kind of damage or degeneration
• It is necessary for passing messages from brain (nervous system) to different organs of body.

- Vitamin B2
Vitamin B2 is involved in many processes in the body and is necessary for normal cell growth and function. It can be found in certain foods such as milk, meat, eggs, nuts, enriched flour, and green vegetables. Some people also take vitamin B2 by mouth to maintain healthy hair, skin, and nails, to slow aging, multiple sclerosis, memory loss including Alzheimer’s disease, high blood pressure, burns, liver disease, and sickle cell anemia.

- Vitamin B3 / Nicotinamide
Nicotinamide is found in many foods including yeast, meat, fish, milk, eggs, green vegetables, beans, and cereal grains. Nicotinamide is taken by mouth for preventing vitamin B3 deficiency and related conditions such as pellagra.

- Vitamin B5
Vitamin B5 is a water-soluble vitamin from the B group of vitamins. It helps produce energy by breaking down fats and carbohydrates, synthesizing cholesterol, forming red blood cells, etc. It also promotes healthy skin, hair, eyes, and liver.

- Vitamin B6
Vitamin B6 is essential vitamin and works in the overall smooth operation of the various internal body functions. Vitamin B6 function:
• This vitamin plays a vital role in the proper functioning of the cardiovascular and also the nervous system
• It also aids in good digestion and immunity development
• It is necessary for proper functioning of brain and is the on which regulates moods.

- Vitamin B12
Vitamin B12 is important for central nervous system function, forming red blood cells, brain development and cognitive function, vitamin B12 also turning the food that you eat into energy. We also need vitamin B12 to form DNA and RNA so that we can make new cells and grow, and for the normal function of the immune system. A vitamin B12 deficiency in children will often present itself with non-specific symptoms such as developmental delays, irritability, lack of appetite, anemia and weakness.

Vitamin C
Vitamin C, also known as ascorbic acid, is a vitamin found in many common foods like citrus fruits, apples, berries, and peppers. Vitamin C is important so your body can form:
• Collagen, blood vessels, cartilage and muscle. This helps to maintain many body tissues, including your skin. It also aids with connective tissue repair and wound healing.
• Neurotransmitters, the chemicals that is important for signaling in the nervous system.
• Carnitine, a chemical that supports the transport and breakdown of fatty acids to generate energy
• Healthy bones and teeth, which are important during your child’s formative years.

Vitamin D
Vitamin D is an important nutrient that works with calcium to help build bones and keep them strong. Vitamin D promotes bone and tooth formation and helps the body absorb calcium. Vitamin D also plays a role in preventing health problems like heart disease, diabetes, osteoporosis, and thinning bones. Our bodies naturally produce vitamin D when we’re outside in the sun. So, many kids get enough vitamin D naturally from being outdoors during daily activities, such as walking, biking, or playing sports. But sometimes the body doesn’t make enough vitamin D, while sunscreen helps protect kids from the sun’s harmful rays, it also blocks some of the sun the body uses to make vitamin D and it can be hard to get enough of this nutrient from our diets because few foods contain it naturally. Good sources include milk and fatty fish like salmon and mackerel. Luckily, many foods are fortified and supplements are available for kids who still need more vitamin D.

Lysine
Lysine is an amino acid (a building block of protein). Unlike some other amino acids, the human body cannot make lysine; therefore it must be eaten in the diet. Source of lysine include meat, dairy, eggs, and some plants such as soy and other legumes. Lysine is important for normal growth and muscle turnover and used to form carnitine, a substance found in most cells of your body.

Glutamic Acid
Glutamic acid is an amino acid used to form proteins. In the body it turns into glutamate. This is a chemical that helps nerve cells in the brain send and receive information from other cells. It may be involved in learning and memory. Glutamic acid may:
• Treat personality and childhood behavioral issues
• Help treat epilepsy and muscular dystrophy
• Treat intellectual disorders

The best strategy for children to get enough vitamins from diet is to choose from a wide variety of foods.
• Emphasize fruits, vegetables, whole grains, and fat-free or low-fat milk and milk products
• Include lean meats, poultry, fish, beans, eggs, and nuts
• Keep diets low in saturated fats, trans fat, cholesterol, salt, and added sugars.

But, there are many reasons that a doctor may recommend these supplements. Some examples include children who are underweight, have restricted diet, or have illnesses that put them at risk for deficiency (low level) of a vitamin.