ContentSIMTOR - 10: Each film coated caplet contains Atorvastatin calcium equivalent to Atorvastatin 10 mg.
SIMTOR - 20: Each film coated caplet contains Atorvastatin calcium equivalent to Atorvastatin 20 mg.
IndicationAdjunct to diet for the reduction of elevated total cholesterol, LDL cholesterol, apolipoprotein B & triglycerides in patients with primary hypercholesterolemia, combined or mixed hyperlipidemia, heterozygous & homozygous familial hypercholesterolemia when diet response & nonpharmacological measures are inadequate. Prevention of cardiovascular complications.
Contra Indication- Hypersensitive
- Patients of the liver or increased serum persistent transamination exceeds 3 times from the normal upper limit.
- Pregnant, breastfeeding, or target pregnant and not using adequate contraception.
DosageInitially 10 mg once daily at range of 10-80 mg once daily. Primary hypercholesterolemia & combined (mixed) hyperlipidemia 10 mg once daily for 2 week & up to 4 week for max response. Homozygous familial hypercholesterolemia 80 mg. Heterozygous familial hypercholesterolemia, Children 10-17 years old, recommended starting dose : 10 mg daily, max 20 mg daily, adjust dose at ≥ 4 weekly intervals.
AttentionPatients with liver disease and myalgia.
Special PrecautionPregnancy and breastfeeding or women who are potentially pregnant.
Adverse ReactionInsomnia, headache, nausea, diarrhea, abdominal pain, dyspepsia, constipation, bloating, myalgia, asthenia, hypoglycemia, hyperglycemia, anorexia, peripheral neuropathy, paresthesia, pancreatitis, vomiting, hepatitis, cholestatic jaundice, alopecia, pruritus, redness, myopathy, myositis, muscle stiffness, impotence.
Drug InteractionAntacida, Cholestipol, Digoxin, Erythromycin/Clarythromycin, Azythromycin, Terfenadine, Oral contraseption, Amlodipine, Protease inhibitor.
Presentation/PackingSIMTOR - 10 : Box @3 blister @ 10 film coated caplet.
SIMTOR - 20 : Box @3 blister @ 10 film coated caplet.